Abstract
The novel heterocyclic pyrimidopyrazolopyrimidine system was synthesised through cyclisation of 4-hydrazinyl-2,6-bis(methylthio)pyrimidine-5-carbonitrile with acetylacetone in high yield. Also, two other tetracyclic systems were synthesised through cyclisation of 4-hydrazinyl-6,8-dimethyl-2-(methylsulfanyl)pyrimido[4′,5′:3,4]pyrazolo[1,5-a]pyrimidine with triethyl orthoformate and sodium nitrite to obtain the pyrimidopyrazolotriazolo pyrimidine and pyrimidopyrazolotetrazolopyrimidine respectively.
Keywords
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