Abstract
The adducts produced in the reaction between alkyl/aryl isocyanides and dialkyl acetylenedicarboxylates were trapped by (2,4-dioxothiazolidin-3-yl)acetic acid to afford highly functionalised dialkyl (E)-2-{[N-alkyl/aryl-2-(2,4-dioxo-1,3-thiazolidin-3-yl)acetamido]carbonyl}but-2-enedioates in good yields. When (5-arylidene-2,4-dioxo-1,3-thiazolidin-3-yl)-acetic acids were employed in these reactions, similar products were obtained.
Keywords
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