Abstract
A series of 2″,3″,4′-triaryl-1′-methyldispiro[indole-3,2′-pyrrolidine-3′,5″-[1,3]thiazolane]-2(1H),4″-dione derivatives were successfully synthesised via a three-component 1,3-dipolar cycloaddition reaction of 2,3,5-trisubstituted-4-thiazolidinones, isatin and sarcosine in refluxing toluene. Such a strategy would provide access to a fast one-pot synthesis of spiroheterocycle in high yields.
Keywords
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