Abstract
A three-component and one-pot reaction between 2,6-diaminopyridine or 1,2-diaminobenzene and ammonium thiocyanate with the subsequent addition of an aroyl chloride afforded the bis-1-(aroyl)-3-(aryl)thiourea in excellent yields. It was important to make the thiocyanate derivatives first and then to use those to prepare the thiourea derivatives.
Keywords
References
1.
Saeed S.
,
Rashid N.
,
Jones P.G.
,
Ali M.
, and
Hussain R.
, Eur J. Med. Chem. , 2010 , 1323 .
2.
Isab A.A.
,
Nawaz S.
,
Saleem M.
,
Altaf M.
,
Monim-al-Mehboob M.
,
Ahmad A.
, and
Evans H.S.
Polyhedron , 2010 , 1251 .
3.
Saeed A.
,
Shaheen U.
,
Hameed A.
, and
Naqvi S.Z.H.
, J. Fluor. Chem. , 2009 , 1028 .
4.
Rauf M.K.
,
Din I.
,
Badshah A.
,
Gielen M.
,
Ebishara M.
,
Vos D.
, and
Ahmed S.
, J. Inorg. Biochem. , 2009 , 1135 .
5.
del Campo R.
,
Criado J.J.
,
Gheorghe R.
,
González F.J.
,
Hermosa M.R.
,
Sanz F.
,
Manzano J.L.
,
Monte E.
, and
Fernández E.R.
, J. Inorg. Biochem. , 2004 , 98 , 1307 .
6.
Solomon V.R.
,
Haq W.
,
Smilkstein M.
,
Srivastava K.
,
Puri S.K.
, and
Katti S.B.
, Eur. J. Med. Chem. , 2010 , 4990 .
7.
Karakuş S.
, and
Rollas S.
, I1 Farmaco , 2002 , 577 .
8.
Awad M.K.
, J. Electroanal. Chem. , 2004 , 219 .
9.
Quraishi M.A.
,
Ansari F.A.
, and
Jamal D.
, Mater. Chem. Phys. , 2002 , 687 .
10.
Arslan H.
,
Külcü N.
, and
Flörke U.
Spectrochim. Acta Part A. , 2006 , 1065 .
11.
Yusof M.S.M.
,
Ayob N.A.C.
,
Kadir M.A.
, and
Yamin B.M.
, Acta Crystallogr. , 2008 , E64 , 937 .
12.
Mohebat R.
,
Mosslemin M.H.
,
Dehghan-Darehshiri A.
, and
Hassanabadi A.
, J. Sulfur Chem. , 2011 , 32 , 557 .