Abstract
A new ent-kaurane diterpenoid named serrin D and seven known compounds were isolated from the aerial parts of Isodon serra. The structure of the new compound was elucidated by various spectroscopic techniques. Five of the compounds were tested for their cytotoxicity towards HL60, SMMC-7721 and Hela cells.
References
1.
Sun H.D.
,
Huang S.X.
, and
Han Q.B.
, Nat. Prod. Rep. , 2006 , 23 , 673 .
2.
Sun H.D.
,
Xu Y.L.
, and
Jiang B.
, Diterpenoids from isodon species , Science Press , Beijing , 2001 , p. 93 .
3.Jiangsu Medicine College , Dictionary of Chinese medicine , Shanghai People's Publishing House , Shanghai, China , 1977 , p. 2511 .
4.
Zhao A.H.
,
Zhang Y.
,
Hu Z.H.
,
Liu J.W.
, and
Jia W.
, Helv. Chim. Acta , 2004 , 87 , 3160 .
5.
Yan F.L.
,
Zhang L.B.
,
Zhang J.X.
, and
Sun H.D.
, J. Chem. Res. , 2007 , 362 .
6.
Li J.C.
,
Liu C.J.
,
An X.Z.
,
Wang M.T.
,
Zhao T.Z.
,
Yu S.Z.
,
Zhao G.S.
, and
Chen R.F.
, Acta Pharmaceut. Sin. , 1982 , 17 , 682 .
7.
Li L.M.
,
Li G.Y.
,
Huang S.X.
,
Li S.H.
,
Zhou Y.
,
Xiao W.L.
,
Lou L.G.
,
Ding L.S.
, and
Sun H.D.
, J. Nat. Prod. , 2006 , 69 , 646 .
8.
Han Q.B.
,
Zhang J.X.
,
Shen Y.H.
, and
Sun H.D.
, Chin J Nat Med. , 2003 , 1 , 16 .
9.
Yang L.B.
,
Huang S.X.
,
Li L.M.
,
Zhao Y.
,
Lei C.
,
Xiao W.L.
,
Pu J.X.
,
Han Q.B.
, and
Sun H.D.
, Helvetica Chim. Acta , 2007 , 90 , 2378 .
10.
Chen Y.Z.
,
Bai G.
,
Meng X.J.
, Acta Chim. Sinica (Engl. Edn ), 1989 , 549 .
11.
Yan F.L.
,
Guo L.Q.
,
Zhang J.X.
,
Bai S.P.
, and
Sun H.D.
, Chin. Chem. Lett. , 2008 , 442 .
12.
Fujita E.
,
Taoka M.
,
Nagao Y.
,
Fujita T.
, J Chem Soc Perkin Trans I. , 1973 , 1760 .
