Abstract
A Prévost reaction of 3,14,19-triacetylandrographolide yielded the 7-ene of 3,14,17,19-tetraacetyl-andrographolide; a plausible mechanism involved in its formation is described.
References
1.
Fujita T.
,
Fujitani R.
,
Takeda Y.
,
Takaishi Y.
,
Yamada T.
,
Kido M.
, and
Miura I.
, Chem. Pharm. Bull. , 1984 , 32 , 2117 .
2.
Varma A.
,
Padh H.
, and
Shrivastava N.
, Evidence-based complementary and alternative medicine , 2011 , doi: 10.1093/ecam/nep135.
3.
Smith A.B.
,
Toder B.H.
,
Carroll P.J.
, and
Donohue J.
, J. Chem. Crystallogr. , 1982 . 12 , 309 .
4.
Jada S.R.
,
McMillan K.
,
Hamzah A.S.
,
Saad M.S.
,
Lajis N.H.
,
Stevens M.F.G.
,
Schwalbe C.H.
, and
Stanslas J.
, J. Chem. Crystallogr. , 2006 , 36 , 93 .
5.
Nanduri S.
,
Nyavanandi V.K.
,
Thunuguntla S.S.R.
,
Kasu S.
,
Pallerla M.K.
,
Ram P.S.
,
Rajagopal S.
,
Kumar R.A.
,
Ramanujam R.
,
Babu J.M.
,
Vyas K.
,
Devi A.S.
,
Reddy G.O.
,
Akella V.
, Bioorg. Med. Chem. Lett. , 2004 , 14 , 4711 .
6.
Aromdee C.
,
Sriubolmas N.
,
Wiyakrutta S.
,
Suebsasna S.
, and
Khunkitti W.
, Arch. Pharm Res. , 2011 , 34 , 71 .
7.
Emmanuvel L.
,
Shaikh T.M.A.
, and
Sudalai A.
, Org. Lett. , 2005 , 7 , 5071 .
8.
Jada S.R.
,
Subur G.S.
,
Matthews C.
,
Hamzah A.S.
,
Lajis N.H.
,
Saad M.S.
,
Stevens M.F.
, and
Stanslas J.
, Phytochemistry , 2007 , 68 , 904 .
