1,3-Dipolar cycloaddition reactions of α-chloro and simple nitrones have been studied with novel α-N-methyl/phenyl furan derivatives as new dipolarophiles. The reactions are found to be highly regioselective to afford single 5-spiro isoxazolidines with high yield in a short reaction time.
PadwaA., and PearsonW. H., Synthetic application of 1,3-dipolar cycloaddition chemistry toward heterocycles and natural products, Wiley, New Jersey, 2003.
2.
CacciariniM., CorderoF. M., FaggiC., and GotiA., Molecules, 2000, 5, 637.
3.
ChakrabortyB., and ChhetriM. S., Indian J. Chem., 2008, 47B, 485.
4.
ChakrabortyB., KafleyS., and ChhetriM. S., J. Chem. Sci., 2010 (in press).
5.
ChakrabortyB., Indian J. Heterocycl. Chem., 2008, 17, 293.
6.
ChakrabortyB., KafleyS., and ChhetriM. S., SharmaP., and GhoshA. R., J. Indian Chem. Soc., 2010 (in press).
7.
ChakrabortyB., KafleyS., ChhetriM. S., and SamantaA., Indian J. Chem., 2010, 49B, 209.
8.
ChakrabortyB., KafleyS., and ChhetriM. S., Indian J. Chem., 2009, 48B, 447.
9.
HoukK.N., SimsJ., and LuskusC. R., J. Am. Chem. Soc, 1973, 95, 7302.
10.
NewtonR., and SavageP. G., Australian J. Chem, 2008, 61, 432.
11.
AouadikK., VidalS., and PralyP. J., Synlett, 2006, 19, 3299.
12.
ChakrabortyB., RaiN., and ChhetriM. S., Rasayan J. Chem., 2010 (in press).
13.
ChakrabortyB., DebrittoP. J., and GhoshA. R., Indian J. Heterocycl. Chem., 1996, 6, 77.
14.
ChakrabortyB., and ChhetriM. S., Indian J. Heterocycl. Chem., 2008, 17, 213.
15.
ChakrabortyB., and ChhetriM. S., Indian J. Heterocycl. Chem., 2008, 18, 201.
16.
AggarwalV.K., GraingerR. S., AdamsH., and SpargoP. L., J. Org. Chem., 1998, 63, 3481.
17.
DeshongP., LiW., KenningtonJ. W., and AmmonH. L., J. Org. Chem., 1991, 56, 1364.
18.
GandolfiR., and GrunangerP., Chem. Heterocycl. Compd N.Y., 1999, 49, 774.
19.
HoffmannW.R., EichlerG., and EndesfelderA., Liebigs Ann. Chem., 2000, 1983.
