Abstract
Pyrazolo[5,1-a]pyrimidines and pyrazolo[5,1-c][1,2,4]triazines containing benzooxazole moiety are synthesised from N-[3-amino-4-(benzoxazol-2-yl)pyrazol-5-yl]phenylamine or its diazonium chloride with the appropriate active methylene compounds. The newly synthesised compounds were elucidated by elemental analysis, spectral data and alternative synthetic route whenever possible.
References
1.
Temiz O.
,
Oren I.
,
Sener E.
,
Yalcin I.
, and
Ucartürk N.
, Il Farmaco , 1998 , 53 , 337 .
2.
Oren I.
,
Temiz O.
,
Yalcin I.
,
Sener E.A.
, and
Altanlar N.
, Eur. J. Pharm. Sci , 1998 , 7 , 153 .
3.
Kumar D.
,
Jacob M.R.
,
Reynolds M.B.
, and
Kerwin S.M.
, Bioorg. Med. Chem. , 2002 , 10 , 3997 .
4.
Kim J.S.
,
Sun Q.
,
Gatto B.
,
Yu Ch.
,
Liu A.
,
Liu L.F.
, and
LaVoie E.
, J. Bioorg. Med. Chem. , 1996 , 4 , 621 .
5.
Hoffman J.M.
,
Smith A.M.
,
Rooney C.S.
,
Fisher T.E.
,
Wai J.S.
,
Thomas C.M.
,
Bamberger D.L.
,
Barne J.L.
,
William T.M.
,
Jobes H.H.
,
Olson B.D.
,
O′Brien J.A.
,
Goldman M.E.
,
Nunberg J.H.
,
Quintero J.C.
,
Schleif W.A.
,
Emini E.A.
, and
Anderson P.S.
, J. Med. Chem. , 1993 , 36 , 953 .
6.
Perrin L.
,
Rakik A.
,
Yearly S.
,
Baumberger C.
,
Kinloch-deLoies S.
,
Pechiere M.
, and
Hirschel B.
, AIDS , 1996 , 10 , 1233 .
7.
Holler M.G.
,
Campo L.F.
,
Brandelli A.
, and
Stefani V.J.
, Photochem. Photobiol. A: Chemistry , 2002 , 149 , 217 .
8.
Laber B.
,
Usunow G.
,
Wiecko E.
,
Franke W.
,
Franke H.
, and
Köhn A.
, Pesticide Biochem. Physiol , 1999 , 63 , 173 .
9.
Dunwell D.W.
, and
Evans D.
, J. Med. Chem. , 1977 , 20 , 797 .
10.
Angustin A.
, and
Dolling W.
, J. Prakt. Chemie. , 1982 , 322 , 324 .