Abstract
Novel pyrrolizidines (1) were synthesised from 1, 3-dipolar cycloaddition of azomethine ylides and dipolarophiles (4). The one-pot three-component reactions were highly diastereoselective and regioselective and were carried out in classical, room temperature ionic liquid and solvent-free microwave-assisted conditions. All methods gave the products in high yields, and their structures were determined by 1H and 13C NMR spectral data and X-ray diffraction.
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