Free accessResearch articleFirst published online 2006-11
An improved synthesis of reduced 9-arylacridine-1,8-diones from 3-amino-5,5-dimethylcyclohex-2-enone,arylaldehydes and 1,3-dicarbonyl compounds in aqueous medium
An improved and green synthesis of 9-arylacridine-1,8-dione derivatives was accomplished by the reaction of 3-amino-5,5-dimethylcyclohex-2-enone, arylaldehydes and 1,3-dicarbonyl compounds in aqueous medium. Novel unsymmetrical 9-arylacridine-1,8-diones differently substituted at the 3 and 6 positions were obtained by this procedure.
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