Abstract
A series of the hydrazones were prepared by the reaction of 4-hydrazino-7,9-dimethylpyrido[3′,2′:4,5]thieno [2,3-d]pyrimidine (1) with monosaccharides, and their acetylation was studied. The oxidative cyclisation of the hydrazones 3a–c gave 3-(Alditol-1-yl)-pyridothienotriazolopyrimidenes 5a–c, whose acetylation was carried out. Also, oxidative cyclisation of arylidenes 7a,b gave the pyridothienotriazolopyrimidines 8a,b.
References
1.
Dobosz M.
,
Pachuta A.
, and
Rekas J.
, Acta Polon. Pharm. , 1993 , 50 , 225 .
2.
Dobosz M.
,
Rekas J.
, and
Pachuta A.
, Acta Polon. Pharm. , 1989 , 46 , 40
3.
Bhat A.R.
,
Varadaraj Bhat G.
, and
Gautham Shenoy G.
J. Pharmacy and Pharmacology , 2001 , 53 , 267 .
4.
El-Ashry El-S. H.
,
Hamid H. A.
,
Mousaad A.
, and
Ramadan E. S.
, J. Chem. Res. , 2002 , 7 , 314 .
5.
Wang Q.
,
Li Z.
,
Yang H.
,
Li F.
,
Ding Z.
, and
Tao F.
, Synthesis , 2003 , 1231 .
6.
Wasfy A.A. F.
, J. Chem. Res. , 2003 , 8 , 457
7.
Wagner G.
,
Bohm N.
, and
Leistner S.
, Pharmazie , 1993 , 48 , 20 ;
8.
Ahmed E.KH.
,
Gohar A. M. N.
, and
Ameen M. A.
, Pharmazie , 2000 , 55 , 31
9.
Bakhite E.A.
,
Radwan Sh. M.
, and
El-Dean A.
, J. Chin. Chem. Soc. , 2000 , 47 , 1105
10.
Ahmed E. Kh.
, Phosphorus, Sulfur, Silicon Relat. Elem. , 2002 , 177 , 1323 .
11.
Bakhite E.A.
,
Abdel-Rahman A. E.
,
Mohamed O. S.
, and
Thabet E. A.
, J. Chem. Res., (S) , 2003 , 58 .
12.
Khattab A. F.
,
El-Sakka I. A.
,
Yassin S. M.
, and
El-Essawy F. A.
, Sulfur Lett. , 1995 , 19 , 23
13.
Christensen U.B.
,
Wamberg M.
,
El-Essawy F. A.
,
Ismail A.
,
Nielsen C. B.
,
Filichev V. V.
,
Jessen C. H
,
Petersen M.
, and
Pedersen E. B.
, Nucleosides, Nucleotides and Nucleic Acids , 2004 , 23 , 207
14.
El-Essawy F.A.
, Nucleosides, Nucleotides and Nucleic Acids , in press;
15.
Khattab A.F.
,
Zahran M. A.
, and
Saif A.
, Synth. Commun. , submitted.
16.
El Ashry El-S. H.
,
Rashed N.
, and
Mousaad A.
, J. Carbohydr. Chem. , 1987 , 6 , 599
17.
Stroh H.-H.
,
Hempel H.
, and
Apel R.
, Chem. Ber. , 1965 , 98 , 2500
18.
Rashed N.
,
Ibrahim El-S I.
, and
El Ashry El-S. H.
, Carbohydr. Res. , 1994 , 254 , 295 ;
19.
Rashed N.
,
Shoukry M.
, and
El Ashry El-S. H.
, Bull. Chem. Soc. Jpn. , 1994 , 67 , 149 ;
20.
Steith J.
,
Boiron A.
,
Frankowski A.
,
Le Nouten D.
,
Rudyk H.
, and
Tschamber T.
, Synthesis , 1994 , 944 ;
21.
Svete J.
,
Golič L.
, and
Stanovnik B.
, J. Heterocycl. Chem. , 1997 , 34 , 1115
22.
Shvedov V.I.
,
Sycheva T. P.
, and
Sakovich T. V.
, Khim. Geterotsikl. Soedin. , 1979 , 10 , 1340 . Chem. Abst. , 92 , (1980) 146648p.