A new application of N-bromophthalimide for the facile oxidation of thiols to their corresponding symmetrical disulfides is described. A wide variety of thiols (aromatic, aliphatic and heterocyclic) were selectively oxidised to their corresponding disulfides with [NBPI] in a mixture of acetone and water under microwave irradiation in a microwave oven at a power output of 650W.
ZolfigolM.A., ShiriniF., Ghorbani-ChoghamaraniA., and GhofraniE., Phosphorus, Sulfur and Silica, 2003, 178, 1477, (j) M.H. Ali and M. Mc-Dermott, Tetrahedron Lett., 2002, 43, 6271;
27.
CaddickS., Tetrahedron, 1995, 51, 10403.
28.
(a) KhazaeiA., and VagheiR. G., Tetrahedron Lett., 2002, 43, 30733.
29.
KhazaeiA., VagheiR. G., and TajbakhshM., Tetrahedron Lett., 2001, 42, 59.
30.
KhazaeiA., and ShirdarrehA., Synth. Commun., 1999, 29, 4079.
31.
KhazaeiA., BridsonK., and PitchardR. G., Cryst. Str. Commun., C5.2001, 970.
32.
KhazaeiA., MehdipourE., and RoodpeymaB., Iran. J. Chem. Chem. Eng., 1995, 14, 77.
33.
KhazaeiA., and ManeshA. A., Synthesis, 2004, 11, 1739.
34.
CoreyE.J., and KimC. U., J. Am. Chem. Soc., 1972, 94, 7586.
35.
FrøyenP., Synth. Commun., 1995, 25, 959.
36.
Charles PoucherJ.The Aldrich Library of NMR Spectra Edition II. 1983, Vol 1, 1,465B.
