4,5-Dihydropyrazolo[4,3-c]quinolines have been synthesised in moderate to good yields from dihydroquinolin-4-ones using the Vilsmeier reagent, under conventional and microwave irradiation conditions.
(a) ElgueroJ., Pyrazoles and their Benzo Derivatives, in Comprehensive Heterocyclic Chemistry; eds. KatritzkyA. R., ReesC. W, Vol. Ed. K. T. Potts, Pergamon Press: New York, 5, 278 (1984). (b) G. Pallazino, L. Cecchi, F. Melani, V. Colotta, G. Filacchioni, C. Martini and A. Lucchini, J. Med. Chem., 30, 1737 (1998).
2.
(a) KellarM.P., SangwanN. K., RastogiS., and AnandN., Ind. J. Chem., 19B, 297 (1980).
3.
YoussefK.M.Al-Azhar Bulletin of Science, 10, 99 (1999).
4.
KalayanaovG.D., KangS. K., CheongH. G., LeeS. G., YumE. K., KimS. S., and ChoiJ. K., Bull. Korean Chem. Soc., 19, 667 (1998).
5.
JutzC., Advances in Organic Chemistry, ed. TaylorE C, John Wiley & Sons, New York, 9, 225 (1976).
6.
JonesG., and StanforthS. P.Org. React., 49, 1 (1997).
7.
SeshadriS., J. Sci. Ind. Res., 32, 128 (1973).
8.
MarsonC.M., Tetrahedron, 48, 3659 (1992).
9.
Meth-CohnO., and StanforthS. P., Comprehensive Organic Synthesis, eds TrostB.M., and FlemingI., Vol. ed. C.H. Heathcock, Pergamon, Oxford, 2, 777 (1991).
10.
(a) Meth-CohnO., and TarnwoskiB., Adv. Heterocycl. Chem., 31, 207 (1982).
11.
Meth-CohnO., Heterocycles, 35, 539 (1993).
12.
(a) MajoV.J., and PerumalP. T., Tetrahedron Lett., 37, 5015 (1996).
13.
MajoV.J., and PerumalP. T., J. Org. Chem., 61, 6523 (1996).
14.
AmareshR.R., and PerumalP. T., Tetrahedron Lett., 38, 7287 (1997).
15.
SelviS., and PerumalP. T., Tetrhedron Lett., 38, 6263 (1997).
16.
MajoV.J., and PerumalP. T., J. Org. Chem., 63, 7136 (1998).
17.
DonellyJ.A., and FarrellD. G., J. Org. Chem., 55, 1757 (1990).
18.
Vogel's, Textbook of Practical Organic Chemistry, 5th edn.
