In recent years, there has been increasing recognition that a number of synthetic polymers which have excellent biodegradability and biocompatibility are materials of pharmaceutical importance in the area of drug delivery technology. The aim of this review is to take a closer look at a few synthetic polymer-based drug delivery systems, specially the aliphatic polyesters, polyamides, polyethers, polyorthoesters, polyanhydrides, polyurethanes, hydrogels and dendritic polymers.
StevensonT.K. W., and SeftonM. V., Trends in Polym Sci, 1994, 2, 98 and references therein.
2.
McCulloschI., and ShalabyS. W., Eds. Tailored Polymeric Materials for Controlled Delivery Systems, Am. Chem. Soc., Washington, DC, 1998.
3.
UhrichK.E., CannizzaroS. M., LangerR. S., and ShakesheffK. M., Chem. Rev., 1999, 99, 3181 and references therein.
4.
LangerR., Acc. Chem. Res., 1993, 26, 537.
5.
SiegelR.A. In Controlled Drug Delivery Challenges and Strategies. Am. Chem. Soc.ParkK., Ed., Washington, DC, 1997.
6.
KostJ., and LapidotS. A., Smart polymers for controlled drug delivery. Handbook of Pharm. Controlled Release Technology, WiseD.L., Brannon-PeppasL., KlibanovA., LangerR., MikosA., PeppasN. A., TrantoloD. J., WnekG. E., and YaszemskiM. J., Eds., Marcel Dekker, Inc.2000, 65 and references therein.
7.
ChandraR., and RustgiR., Prog. Polym. Sci., 1998, 23, 1273.
8.
BirnbaumD.T., and Brannon-PeppasL., Polymer News, 2002, 27, 13
9.
LanzaR.P., LangerR., and ChickW. L., Principles of Tissue Eng., R.G. Landes Co. and Academic Press: Austin, TX, 1997.
10.
WongW.H., and MooneyD. J., In Synthetic Biodegradable Polymer Scaffolds; AtataMooney, Eds.; Birkhauser: Boston, MA, 1997.
11.
GriffithL.G., Acta Mater., 2000, 48263.
12.
VertM., LiS. M., and GarreauH., J. Biomater. Sci., Polym. Ed., 1994, 6639.
13.
Ravi KumarM.N. V., J. Pharm. Pharmaceut. Sci, 2000, 3334.
14.
VertM., SchwarchG., and CoudaneJ., J. Macromol. Sci. Pure Appl. Chem., 1995, A32787.
15.
AndreopoulosA.G., Clin. Mater., 1994, 1589.
16.
LeCorreP., RyttingJ. H., GajanV., ChevanneF., and LeVergeR., J. Microencapsulation, 1997, 14243.
17.
NamS.Y., LeeK. H., and ParkT. G., Polym. Prep., 1998, 39216.
18.
MuL., and FengS. S., J. Controlled Rel., 2003, 8633.
19.
PittC.G., and SchindlerA., Prog. Contraceptive Delv. Systems, 1980, 1, 17.
20.
PittC.G., In Biodegradable Polymers as drug delivery systems.ChasinM., and LangerR., Eds., Marcel Dekker, New York, 1990, 71.
21.
(a) PittC.G.J. Appl. Polym. Sci, 1981, 26, 3779.
22.
GuzmanM., MolpreceresJ., GarciaF., and AberturasM. R., J. Microencapsulation, 1996, 1325.
23.
JameelaS.R., SumaN., and JayakrishnanA., J. Biomater. Sci., 1997, 8457.
24.
YouanB.B. C., BenoitM. A., BarasB., RiveauG., and GillardJ., J. Control. Rel., 1997, 48, 339.
25.
(a) MariaR., and AlbertssonA. C., Macromolecular Symposia, 2001, 175, 11.
26.
GuerraG.D., CerraiP., TricoliM., and MaltintiS., J. Mater. Sci: Materials in Medicine, 2001, 12, 313.
27.
HellerJ., PenhaleD. W. H., and HelwingR. F., J. Polym. Sci, Polym. Lett. Ed., 1980, 18, 619.
28.
NgS.Y., VandammeT., TaylorM. S., and HellerJ., Macromolecules, 1997, 30, 770.
29.
BernatchezS.F., MerkliA., TabatabayC., GurnyR., ZhaoQ. H., AndersonJ. M., and HellerJ., J. Biomed. Mater. Res., 1993, 27, 677.
30.
GopferichA., and TessmarJ., Adv. Drug Delivery Rev.2002, 54, 911 and references therein.
31.
DombA.J., AmselemS., ShahJ., and ManiarM., In Adv. Polym. Sci., PeppasN.A., and LangerR., Eds. Springer, Berlin1992, 107, 93.
IskakovR., BatyrbekovE., LeonovaM. B., and ZhubanovB. A., J. Appl. Polym. Sci, 2000, 75, 35.
58.
BatyrbekovE.O., RukhinaL. B., ZubanovB. A., BekmukhamedovaN. F., and SmailovaG. A., Polym. Int., 1997, 43, 317.
59.
PeppasN.A., Ed; Hydrogels in Medicine and Phermacy; Vol I, II, III, CRC: Boca Raton, FL, (1986).
60.
KimS.W., BaeY. H., and OkanoT., Pharm. Res., 1992, 9, 283.
61.
PeppasN.A., BuresP., LeobandungW., and IchikawaH., Eur. J. Pharm. Biopharm., 2000, 50, 27.
62.
(a) ZahoX., and HarrisJ. M., J. Pharm. Sci, 1998, 87, 1450 and references therein.
63.
ParkJ.H., and BaeY. H., Biomaterials, 2002, 23, 1797.
64.
(a) HoffmanA.S., SaitoH., and HarrisJ. M., Drug delivery from biodegradable PEG hydrogels with Schiff base linkages. Proceedings of the International symposium on controlled release of bioactive materials, USA, 24th, 565 (1997).
65.
ParkK., ShalabyW. S. W., and ParkH.Biodegradable Hydrogels for Drug Delivery, Technomic, Lancaster, PA (1993).
66.
StaytonP.S., ShimobojiT., LongC., ChilkotiA., ChenG. H., HarrisJ. M., and HoffmanA. S., Nature, 1995, 378, 472.
67.
PeppasN.A., and WrightS. L., Eur. J. Pharm. Biopharm, 1998, 46, 15.
68.
MarklandP., ZhangY., AmidonG. L., and YangV. C., J. Biomed. Mater. Res., 1999, 47, 595.
69.
DorskiC.M., DoyleF. J., and PeppasN. A., Polym. Mater. Sci. Eng. Proc., 1997, 76, 281.
70.
EinersonN.J., StevensK. R., and KaoW. J., Biomaterials, 2003, 24, 509; S.H. Gehrike, J.F. McBride, S.M. O'Connor, H. Zhu and J.P. Fisher, Polym. Mater. Sci. Engng, 1997, 76,234.
71.
ZhuoR.-X., and LiW., J. Polym. Sci, Part-A, Polym. Chem., 2003, 41, 152.
72.
LiuM., and FrechetJ. M. J., Pharm. Sci. Technol. Today, 1999, 2, 393.
73.
TwymanL.J., BeezerA. E., EsfandR., HardyM. J., and MitchellJ. C., Tetrahedron Lett., 1999, 40, 1743.
74.
IhreH.R., Padilla De JesusO. L., SzokaF. C.Jr., and FrechetJ. M. J., Bioconjugate Chem., 2002, 13, 443.
75.
TomaliaD.A., NaylorA. M., and GoddardW. A., Angew Chem. Int. Ed. Engl., 1990, 29, 138.
76.
MalikN., WiwattanapatapeeR., KlopschR., LorenzK., FreyH., WeenerJ. W., MeijerE. W., PaulusW., and DuncanR., J. Controlled Rel., 2000, 65, 133.
77.
(a) LiuM., KonoK., and FrechetJ. M. J., J. Polym. Sci. Part-A, Polym. Chem., 1999, 37, 3492.
78.
KojmaC., KonoK., MaruyamaK., and TakagishiT., Bioconjugate Chem., 2000, 11, 910.
79.
BaarsM.W., KleppingerR., KochM. H. J., YeuS. L., and MeijerE. W., Angew Chem. Int. Ed., 2000, 39, 1285.
