Abstract
A one-pot synthesis of 1,3,4-trisubstituted imidazolin-2-ones, from the reaction of α-aminoacetophenone hydrochlorides with aryl isocyanates in good yields, is described.
References
1.
Evans D.R.
,
Herbert R. B.
, and
Baumberg S.
, Tetrahedron Lett. , 1995 , 36 , 2351 .
2.
Parmée E.R.
, and
Naylor E. M.
, Bioorg. Med. Chem. Lett. , 1999 , 9 , 749 .
3.
Naylor E.M.
, and
Parmée E. R.
, Bioorg. Med. Chem. Lett. , 1999 , 9 , 755 .
4.
Andres J.I.
, and
Alonso J. M.
, Bioorg. Med. Chem. Lett. , 2002 , 12 , 653 .
5.
Devan B.
, and
Rajagopalan K.
, Tetrahedron Lett. , 1994 , 35 , 1585 .
6.
De Kimpe N
, and
De Cock W.
, J. Heterocyclic Chem. , 1996 , 33 , 1179 .
7.
Carling R.W.
, and
Moore K. W.
, J. Med. Chem. , 1999 , 42 , 2706 .
8.
Coşkum N.
, Tetrahedron , 1999 , 55 , 475 .