A comparative study on the synthesis of 3′-aryl-3-methyl/2,3-dimethylspiro[6,7,8,9-tetrahydro-5 H -benzo[a]cyclohepten-5,2′-(tetrahydro[1,3] thiazolane)]-4′-ones using microwave irradiation and conventional methods
Free accessResearch articleFirst published online April, 2004
A comparative study on the synthesis of 3′-aryl-3-methyl/2,3-dimethylspiro[6,7,8,9-tetrahydro-5 H -benzo[a]cyclohepten-5,2′-(tetrahydro[1,3] thiazolane)]-4′-ones using microwave irradiation and conventional methods
A convenient one pot synthesis of 3′-aryl-3-methyl/2,3-dimethylspiro[6,7,8,9-tetrahydro-5H-benzo[a]cyclohepten-5,2′-(tetrahydro[1,3]thiazolane)-4′-ones under microwave irradiation, as well as conventional methods, is described. Microwave irradiation has resulted in the reduction of time from hours to minutes. Antimicrobial activity of these compounds was studied and that some compounds gave positive results.
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