Chemical investigation of Clerodendrum indicum has resulted in the isolation of clerodendrone, a new member of hydroquinone diterpenoids (which are rare in the investigated family, Verbenaceae). The compound was characterised from its spectral (1D and 2D NMR) data and chemical reactions and was found to contain an uncommon structural pattern with beta-methyl dihydrofuran moiety.
Part 38 in the series, Studies on Phytochemicals, for part 37 see RameshC., RavindranathN., DasB., PrabhakaranA., JagadishB., KashinathamA., and McMorrisC.J. Nat. Prod.2002(submitted); IICT Communication No. 4597.
2.
Anonymous, Wealth of India, Raw materials, Vol.II, C.S.I.R., New Delhi, 1950, 231–232.
3.
SubramanianS.S., and NairA. G. R.Phychemistry, 1973, 12, 1195.
4.
JunT., Qin ShiS., Zhong WenL., and Han DongS., Chin. Chem. Lett.1996, 7, 279.
5.
IkutaA., and ItokawaH.Phytochemistry, 1988, 27, 2813.
6.
SamaraweeraU., SotheswaranS., and SultanbawaM. U.Phytochemistry1983, 22, 565.
7.
Al-HazimiH.S. M., MianaG. A., DeepM. S. H.Phytochemistry1987, 26, 1091.
8.
(a) SchmidJ.M., RuediP., EugsterC. H.Helv. Chem. Acta.1982, 65, 2136; (b). M. J. S. Cuadrado, M. R. Bruno, M. C. De La Torre, F. Piozzi, G. Savona and B. Rodriguez Phytochemistry 1992, 31, 1697.
9.
(a). SinghR., and PrakashL., Pharmazie1983, 38, 565; (b). A. -C. Dorsaz, A. Marston, H. Stoeckli - Evans, J. D. Msonthi and K. Hostettmann Helv. Chem. Acta. 1985, 68, 1605.
10.
CarreirasM.C., RodriguezB., De la TorreM., PeralesA., TorresM. R., SavonaG., and PiozziF.Tetrahedron1990, 46, 847.
11.
LindyM.E.Practical Introduce to Microbiology, E & F.N. Spon Ltd., 1962, p. 177.
