A series of 5-benzylidenethiazolidine-2,4-diones was synthesised by the Knoevenagel condensation of aromatic aldehydes with thiazolidine-2,4-dione in the presence of catalytic amounts of piperidine and acetic acid under microwave irradiation without solvent in good yields.
UnanstP.C., ConnorD. T., CetenkoW. A., SorensonR. J., KostlanC. R., SircarJ. C., WrighlC. D., SchrierD. J., and DyerR. D., J. Med. Chem., 1994, 37, 322
4.
(a) CaddickS., Tetrahedron, 1995, 51, 10403; (b) R. A. Abramovitch, Org. Prep. Proc. Int., 1991, 23, 683; (c) A. Loupy, A. Petit, J. Hamelin, F. Texier-Boullet, P. Jacqualt and D. Mathe, Synthesis, 1998, 1213; (d) R. S. Varma, Green Chem., 1999, 1, 43; (e) D. M. P. Mingos and D. R. Baghurst, Chem. Soc. Rev., 1991, 20, 1
5.
GilesR.G., LewisN. J., QuickJ. K., SasseM. J., UrquhartM. W. J., and YoussefL., Tetrahedron, 2000, 56, 4531
6.
LevshinI.B., TsurkanI. B., V'yunovK. A., and GinakA. I., Zh. Prikl. Khim., 1983, 56, 1453
7.
ZubenkoV.G., Trudy L'vov. Med. Inst., 1957, 12, 80, CA 1960,54:21059
8.
MusialL., and StaniecJ., Roczniki Chem.1965, 39, 839, CA 1966, 64: 3516a