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Abstract

Meldrum's acid reacted with an aryl isothiocynate and alkyl halides to afford the 5-(arylamino(alkylthio)methylene)-5-methylthio-2,2-dimethyl-1,3-dioxane-4,6-diones and the compounds underwent thermal cyclization to give the 4-2-arylthio-4(1H)-quinolones

Keywords

5-(arylamino(alkylthio)methylene)-2,2-dimethyl-1,3-dioxane-4,6-diones

References

(a) McNab

, Chem. Soc. Rev. 1978, 7, 345; (b) B. C Chen, Heterocycles, 1991, 32, 529-597

Chen

B. C.

, and Huang

, Synthesis, 1987, 482

Huang

, and Chen

B. C.

, Synthesis, 1987, 480.

Huang

, and Chen

B. C.

Synthesis, 1986, 967

F. C.

, Chen

B. C.

, and Huang

Synthesis, 1989, 317;

Convenient synthesis of 5-(Arylamino(Alkylthio)Methylene)-2,2-Dimethyl-1,3-Dioxane-4,6-Diones and 2-Arylthio-4-Quinolones

Abstract

Keywords

References