Electrophilic Substitution Reactions of Indoles with Carbonyl Compounds Using Ceric Ammonium Nitrate: A Novel and Efficient Method for the Synthesis of Di- and Tri-Indolylmethanes 1 †
Ceric ammonium nitrate (CAN) is used to catalyse the electrophilic substitution reactions of indoles with carbonyl compounds at room temperature to produce di- and tri-indolylmethanes in high yields.
Part 11 in the series ‘Studies on Novel Synthetic Methodologies’, for Part 10 see RavindranathN., RameshC., and DasB.; Synlett, 20011777. IICT Communication No. 4667.
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