A Novel One-Pot Synthesis of Cyclopentanol Derivatives from Aldehydes and α-Haloketones by Samarium (III) Iodide and Samarium (II) Iodide Mediated Cascade Reactions †
Free accessOtherFirst published online March, 2001
A Novel One-Pot Synthesis of Cyclopentanol Derivatives from Aldehydes and α-Haloketones by Samarium (III) Iodide and Samarium (II) Iodide Mediated Cascade Reactions †
Aldehydes can react with α-haloketones promoted by Sml3, to give α,β-unsaturated ketones, then, by adding powdered samarium to the reaction mixture, these undergo reductive cyclodimerisation to afford cyclopentanol derivatives under mild conditions
