Bernumicine and bernumidine are two alkaloids extracted from Berberis nummularia. Their total synthesis has been completed and it has been shown that the configuration of the stereogenic carbon of both is (R).
TeitelS., O'BrienJ., PoolW., BrossiA., J. Med. Chem., 1974, 17, 134; T. Fuji, K. Yamada, D. Minami, S. Yoshifuji, M. Ohba, Chem. Pharm. Bull. 1983, 31, 2583.
AltomareA., CascaranoM., GiacovazzoC., GuagliardiA., SIR92 – a program for automatic solution of crystal structures by direct methods, J. Appl. Cryst., 1993, 26, 343
14.
teXsan: Single Crystal Structure Analysis Software Version 1.7 (1995). Molecular Structure Corporation, The Woodlands, TX. 77381.
