The Metal Template Effect on O -Alkylation of Hexahomotrioxacalix[3]arene with 4-(chloromethyl)pyridine to afford tris[(4-pyridylmethyl)oxy]hexahomotrioxacalix[3]arenes and their conformational studies
Free accessResearch articleFirst published online January, 2000
The Metal Template Effect on O -Alkylation of Hexahomotrioxacalix[3]arene with 4-(chloromethyl)pyridine to afford tris[(4-pyridylmethyl)oxy]hexahomotrioxacalix[3]arenes and their conformational studies
O-Alkylation of the flexible macrocycle 1 with 4-(chloromethyl)pyridine gave di- and tri-O-alkylated products with cone or partial-cone conformation which ratio was affected by NaH or alkali metal carbonates used as a base.
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