Abstract
Summary
1. Optimum conditions for hydrolysis of phosphoethanolamine by tissue homogenates have been determined to be: veronal-acetate, pH 4.5, and veronal, pH 9.0, Mg++. 5 × 103 M. 2. Concentration of phosphoethanolamine was determined in 6 rat and rabbit tissues as well as 2 transplantable tumors. 3. Alkaline phosphatase of the various extracts readily hydrolysed the ester and at greater rates than acid phosphatase. 4. Phosphoethanolamine was more readily hydrolysed by acid phosphatase of human prostate than of any other tissue examined. 5. Dilution and dialysis experiments with liver indicate there is a competition for phosphatase between phosphoethanolamine and other phosphate esters present in liver.
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