Abstract
Summary and Conclusions
Intraperitoneal injection of human erythrocytes in pre-natal or neo-natal rats reduces antibody response to subsequent immunizations. No ill-effects were observed in any of the experimental animals surviving the initial injection and there was no difference in growth rate from the uninjected controls. These studies suggest that it is possible to confer type specific tolerance to subsequent immunization of A and D (Rho) antigens of human erythrocytes.
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