Abstract
Summary
A method for purification of the rheumatoid factor has been presented. A euglobulin fraction of serum was chromatographed on DEAE cellulose. The resulting active fraction was further chromatographed on carboxymethyl cellulose to yield a preparation which contained more than 90% of a component with a sedimentation coefficient of 18.8. Relative specific activities at successive stages of purification were determined. Concentration dependence data for the sedimentation coefficient were obtained.
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