Abstract
Summary
Acute pharmacologic comparisons have been made of N, N-dimethyl, 2- chloro-2-phenylethylamine (DMEA) and N, N-dimethyl, 2-chloro-2-phenyl-1-methylethyl-amine (M-DMEA). The 2 differed in immonium ring stability in vitro, speed of onset and degree of adrenergic blocking activity, and production of atropine-resistant salivation. There was no relationship between duration of effects and in vitro life of intermediate ethyl-eneimmonium forms.
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