Abstract
Summary
TPN+ content of erythrocytes of primaquine-sensitive males is greater than that of erythrocytes of normal males. The increase in TPN+ may be explained by two known factors: 1) decrease in glucoses-phosphate dehydrogenase activity, and 2) increased glutathione reductase activity in primaquine-sensitive erythrocytes. The mean values of DPN+ content of erythrocytes in the two populations studied were different, but the values showed considerable overlap. Our current studies concern the effect of drug administration on both oxidized and reduced coenzymes in normal and primaquine-sensitive erythrocytes from both males and females.
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