Studies in Leukemia: XI. Active Immunization of C3H x 101 Mice Against Induction of Leukemia. ∗

Abstract

Summary

1. Leukemic and non-leukemic cell-free brain filtrates were irradiated with ultraviolet light. C3H x 101 mice were actively immunized by subcutaneous inoculations. 2. Active immunization with ultraviolet irradiated leukemic cell-free brain filtrate gave significant protection against challenge of leukemic cell-free brain filtrate. 3. Active immunization with ultraviolet irradiated cell-free brain filtrates did not protect against challenge of a high concentration of tumor-cell suspension.