Osmotic Resistance and Post-Transfusion Survival of Human Erythrocytes Stored in the Presence of α1 -Tocopheryl Disodium Phosphate

Abstract

Summary

Presence of 10^-3M disodium α1-tocopheryl phosphate in human ACD-blood greatly retards rate of decrease in osmotic resistance of the erythrocytes that occurs on storage at 4°C. Post-transfusion survival of erythrocytes from blood stored in this manner is no better than that of erythrocytes from blood stored in ACD alone. It is emphasized that enhanced osmotic resistance of preserved blood is not necessarily related to enhanced post-transfusion survival.