Abstract
Summary
C57BL and LAF1 mice became hyperpigmented in the extremities when exposed daily to gamma radiation. This process was not significantly altered by adrenalectomy, castration or daily treatment with ACTH. Hypophysectomized black rats, X-irradiated weekly, developed hyperpigmentation at the same rate as controls. Although it would appear that induction of hyperpigmentation by radiations is largely free of endocrine control, daily treatment of gamma irradiated mice with large doses of cortisone will suppress pigment formation.
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