Abstract
Summary
A single injection of exudate from Murphy rat lymphosarcoma produced polyarthritis and elevated polysaccharide/protein ratios of the serum. In a later series of experiments the incidence of arthritis was much less. When arthritis was produced cortisol inhibited the incidence and severity of the arthritic lesions and partially reversed the shift in polysaccharide/protein ratio. Phenylbutazone had no consistent effect on polyarthritis or serum ratios.
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