Abstract
Conclusions
1) Chloride appears to be the most important anion in oral sodium solutions used for prevention and treatment of experimental burn shock in mice. 2) Citrate, acetate, bicarbonate, and lactate are far less effective than chloride, and may be toxic in large doses. 3) There is no sanctity in the customary 93:47 or higher meq ratio between chloride and other ions in oral electrolyte solutions used in these experiments. 4) Gluconate appears to serve as a partial substitute for chloride, and it lends palatability; experimental and clinical studies are indicated on gluconate metabolism in man.
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