Abstract
Summary
Normal, malignant, and transformed cell lines have been studied for variations in 3 different enzyme activities, GO-T, GP-T, and LD. Only LD activity changed during the growth period. The enzyme activity both in the cells and in the fluid bathing them was greatly increased in the malignant cell lines and in 2 transformed lines, in contrast to the normal cell lines and the conjunctiva cell line where large quantities did not appear in the media. The increase in LD activity was found to be related to the cellular growth rate rather than to be a characteristic of the cell, since the normal cells in most instances were found to contain more enzyme activity per cell than the malignant ones.
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