Abstract
Summary
The transforming agent prepared from myxoma virus (TAM) is resistant to heat, to ether extraction, and to mild enzymatic digestion but is inactivated by the photodynamic action of toluidine blue. TAM particles can be sedimented by ultracentrifugation (Spinco). TAM becomes attached to rabbit kidney cells in 15 minutes, when inoculated by itself, is not destroyed by incubation in tissue cultures for 48 hours at 36°, and can be added before or after live fibroma virus in transformation experiments. The transforming agent is not immunogenic against myxoma virus in rabbits.
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