Abstract
Summary
Formalinized erythrocytes exposed to purified DNA under the proper conditions can then be specifically agglutinated with antiserum, which has been prepared against the DNA-protein complex. Inhibition of the reaction by homologous DNA is strong evidence that agglutination is an antigen-antibody reaction and not merely a non-specific agglutination. The removal of this reactivity by desoxyribonuclease lends further support to the belief that DNA is functioning as the hapten. Trypsin does not alter the agglutination reaction.
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