Abstract
Summary
1. Normal rabbits were able to rid their plasma of excess cholesterol just as rapidly after such cholesterol was administered in the form of rabbit hypercholesteremic serum, as when administered in the form of rat hypercholesteremic serum. 2. Hypercholesteremic rabbits whose plasma level of cholesterol was reduced by exchange transfusions exhibited a return to higher levels in succeeding days. 3. Normocholesteremic rabbits whose level of cholesterol was elevated by exchange transfusions quickly reverted to their previous normocholesteremic status. 4. These facts suggest that the chronic discharge of previously stored tissue cholesterol is responsible for the long persistent hypercholesteremia in the rabbit after cessation of cholesterol feeding.
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