Abstract
Summary
Small pieces of mouse kidney, liver, and whole adrenal glands were allowed to autolyze in incubator for varying times before fixation. Nuclear sizes were measured and compared with control tissues that had been mounted and stained together on the same slide. Nuclear volumes increased about 70% over controls during the first 30 to 60 minutes of autolysis in kidney and adrenal cortex. This was followed by a decrease in volumes eventually leveling off to about half that of the control in the kidney and the same as the control in adrenal cortex. A comparison of frequency distribution of nuclear volumes in liver revealed no differences between autolyzed samples and the control samples.
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