Abstract
Summary
Arthus reactivity was diminished or abolished in mice and guinea pigs showing protracted anaphylactic shock. Mice were sensitized to 2 unrelated antigens, then injected with one of these antigens into the lip or footpad and with the other antigen intravenously. The reaction in the lip or footpad was scant or did not occur. Guinea pigs in protracted anaphylactic shock after subcutaneous injection of antigen did not react locally 4 hours after skin tests with an unrelated antigen to which they were also sensitive. Reactions were observable 24 hours after intracutaneous injections; these differed grossly from those found in control guinea pigs not injected with subcutaneous shocking doses of antigen.
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