Abstract
Summary
1. The edema of the rat foot produced by serotonin injection as influenced by aminopyrine has been quantitated circumferimetrically and observationally. 2. The data obtained by circumferimetry have been analyzed by means of response metameter, Y2 = 100 log 2 hr reading/Zero hr reading. 3. Results obtained by circumferimeter can serve as basis of quantitative anti-edema assay with inherent precision A = .57. 4. Subjective scores either alone or in combination with circumferimetrically derived data are less satisfactory for use in this assay.
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