Abstract
Summary
1) A chloramphenicol-resistant strain of Staphylococcus pyogenes (Strain R) has been found less tolerant to NaCl and KCl than its chloramphenicol-sensitive counterpart (Strain S). The restoration of salt-tolerance in Strain R by serial sub-cultivation in increasing concentrations of salts resulted in a decrease in resistance to chloramphenicol. 2) The combined effects of chloramphenicol and salts on both Strains S and R were additive in most concentrations and frequently synergistic.
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