Action of Colicines on Shigella boydii and on their Rough and Mucoid Variants

Abstract

Summary

In 58 experiments involving comparisons of 6 smooth parent cultures of various Sh. boydii serotypes and their corresponding non-S variants, the variants were significantly more sensitive to colicine action than the smooth parent strains. Reversal of the culture from the non-S to the S form was accomplished by use of kinetin, and the “transformed” cultures reflected, in part, the colicine spectrum of the original S parent culture and in part the spectrum of the non-S variants from which the “transformed” S cultures were immediately derived.