Abstract
Summary
1) The normal lipid composition of chick skin and of chorioallantoic membrane is reported. Evidence is presented which indicates that there is an alteration in lipid metabolism of these tissues when infected with fowlpox virus. 2) This evidence consists of: (1) On dry weight basis, infection of the chick resulted in decreased amount of total skin lipids, the greater part referable to total fatty acid fraction. The level of esterified cholesterol became elevated. (2) Partition studies of chick skin lipid revealed that concentration of total cholesterol, esterified cholesterol and free fatty acids increased in contrast to lowered total fatty acid values. (3) Dry weight analyses of infected chorioallantoic membrane demonstrated a general increase in lipid components with the exception of free cholesterol and phospholipid, which decreased and were unchanged, respectively. (4) Partition of CAM lipid disclosed that free cholesterol and phospholipid decreased in percentage while esterified cholesterol exhibited a 15-fold increase during infection.
Get full access to this article
View all access options for this article.