Abstract
Summary
Administration of typhoid and paratyphoid vaccine as well as Piromen caused rapid clearing of alimentary lipemia in dogs which developed fever of 103°F or more. This phenomenon appears to be unspecific and seemingly due to marked temperature rise induced by these agents, since no change of turbidity occurred in animals with fever below 103°F. Administration of protamine sulfate to vaccine-treated dogs prevented clearing of the lipemic sera despite a marked elevation of temperature. No clearing of turbidity occurred when the lactescent sera were kept in water bath at 105°F for 24 hours. It is suggested that high body temperature in the dog may cause release of heparin or a heparin-like substance to produce a lipemia clearing factor.
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