Abstract
Summary
Specimens of skin, tendon, and cortical bone from the calf were exhaustively demineralized with EDTA at pH 7.4. These tissues were then equilibrated with solutions of varying calcium and phosphorus content. All 3 tissues, presumably because of their collagen content, were able to induce formation of hydroxy apatite crystals from otherwise stable solutions. In contrast to skin and tendon, bone removed calcium from all solutions, but all three tissues were equally efficient in crystal seeding.
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