Abstract
Summary
As measured by one-stage prothrombin time, mixtures of various body tissues may have thromboplastin activity greater than that of either of the tissues in the mixture. A marked synergistic action as to thromboplastin activity occurs between body tissue extracts and Russell viper venom. This effect is absent if the plasma lacks either prothrombin or labile factor (factor V). The thromboplastin activity of Russell viper venom is not influenced by the lack of stable factor (factor VII) in contrast to the high sensitivity observed with rabbit brain thromboplastin.
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