Abstract
Summary
The synthesis and characteristics of a series of branched chain fatty acid ester of cholesterol are described. The hydrolysis of these esters by pancreatic cholesterol esterase was determined under standard conditions. The branched chain acid esters were hydrolyzed at lower rates than corresponding n-acid esters. The closer the location of the branch to the ester bond, the greater the depression in activity. Esters with ethyl groups on carbon 2 were hydrolyzed at a slower rate than those with methyl groups at this location.
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