Abstract
Summary
1. Adrenal glands from golden hamster fetuses, transplanted homologously into cheek pouches of adult hamsters which were adrenalectomized 22 days after transplantation, maintained the untreated hosts for at least 4 times the expected survival time of adrenalectomized and untreated hamsters without transplants. 2. When the adrenal transplants were excised from surviving hosts, after 67 to 154 days in the cheek pouch, the hosts died within 6 days. 3. Microscopic appearance of healthy cortical cells with some indication of adult arrangement in zones and cords, supported the physiological evidence for growth, differentiation and function of the adrenal transplants. This is the first known instance of successful adrenocortical transplantation in the hamster.
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