Abstract
Summary
Certain benzimidazole. benzothiazole, indole, and quinoline derivatives, and auramine, inhibit destruction of the azo dye. 4-dimethylaminoazobenzene, by liver homogenates. This inhibition can be partially overcome by addition of riboflavin adenine dinucleotide and to a lesser extent by riboflavin phosphate. Correlation of inhibition of in vitro dye destruction and of heme synthesis by avian erythrocytes with the anti-azo dye carcinogenic effect of certain benzimidazoles is discussed.
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