Abstract
Summary
Respiration of liver homogenates derived from adult male rats exposed to cold for about one month was studied. Cold exposure led to 1) an increased endogenous metabolism and 2) increased rates when citrate, isocitrate, αL-ketoglutarate, succinate, fumarate, malate, glutamate and βT-hydroxybutyrate were present as substrates. No change in rate was observed when lactate was present as substrate. Differences were also found in both the magnitude and pattern of in vitro oxidations following cold exposure.
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